产品说明
应用
Acylase I from porcine kidney has been used to study the acylase I-catalyzed deacetylation of various S-alkyl-N-acetyl-L-cysteines and their carbon and oxygen analogues . Acylase I may be useful to catalyze N-acetyl amino acids to enantiomerically pure L-amino acids .
包装
1, 10 g in poly bottle
生化/生理作用
Acylase I is a zinc metalloprotein that catalyzes the kinetic resolution of unnatural and rarely occurring α-amino acids. Its enantioselectivity for the hydrolysis of N-acyl L-α-amino acids is nearly absolute, yet it accepts substrates having a wide range of structure and functionality. Acylase I catalyzes the deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. n-Butylmalonic acid is an inhibitor of acylase I. S-alkyl-N-acetyl-L-cysteines with short (C0-C3) and unbranched S-alkyl substituents have been found to be good acylase I substrates.
单位定义
One unit will hydrolyze 1.0 μmole of N-acetyl-
分析说明
Protein determined by biuret.
基本信息
| 酶学委员会(EC)编号 | 3.5.1.14 ( BRENDA | IUBMB ) |
| EC 号 | 232-732-3 |
| MDL编号 | MFCD00081285 |
| NACRES | NA.54 |
产品性质
| 质量水平 | 200 |
| 类型 | Grade II |
| 形式 | salt-free, lyophilized powder |
| specific activity | 500-1,500 units/mg protein |
| UniProt登记号 | P37111 |
| 储存温度 | −20℃ |
| Gene Information | pig ... ACY1(396930) |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H315 - H319 - H334 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
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