产品说明
应用
Sulfobromophthalein disodium salt hydrate has been used as a positive control to study the interaction of 11-keto-β-boswellic acid (KBA) and 3-acetyl-11-keto-β-boswellic acid (AKBA) with organic anion transporter OATP1B3.
包装
5 g in glass bottle
生化/生理作用
Sulfobromophthalein (BSP) is a high affinity organic ion substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein 2 (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20.
基本信息
| 经验(实验)分子式 | C20H8Br4Na2O10S2 · xH2O |
| 分子量 | 838.00 (anhydrous basis) |
| EC 号 | 200-761-0 |
| MDL编号 | MFCD00150017 |
| PubChem化学物质编号 | 24899433 |
| NACRES | NA.47 |
产品性质
| 质量水平 | 200 |
| 溶解性 | water: 50 mg/mL, clear to hazy |
| application(s) | diagnostic assay manufacturing hematology histology |
| 储存温度 | room temp |
| SMILES string | [Na+].[Na+].[H]O[H].Oc1ccc(cc1S([O-])(=O)=O)C2(OC(=O)c3c(Br)c(Br)c(Br)c(Br)c23)c4ccc(O)c(c4)S([O-])(=O)=O |
| InChI | 1S/C20H10Br4O10S2.2Na.H2O/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33;;;/h1-6,25-26H,(H,28,29,30)(H,31,32,33);;;1H2/q;2*+1;/p-2 |
| InChI key | CDTNUNQQEUGDSD-UHFFFAOYSA-L |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H317 - H334 |
| 预防措施声明 | P261 - P280 - P342 + P311 |
| 危险分类 | Resp. Sens. 1 - Skin Sens. 1 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
