产品说明
包装
10, 100, 500 mg in ampule
1 g in ampule
Sealed ampule.
生化/生理作用
Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, contraction, chemotaxis, and cell proliferation, differentiation and apoptosis. AA has been demonstrated to bind to the α subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.
基本信息
| 经验(实验)分子式 | C22H36O2 |
| 分子量 | 332.52 |
| MDL编号 | MFCD00038340 |
| PubChem化学物质编号 | 24891398 |
| NACRES | NA.25 |
产品性质
| 生物来源 | fungus |
| 质量水平 | 100 |
| 测定 | ≥98.5% (GC) |
| 形式 | liquid |
| 官能团 | ester |
| 运输 | ambient |
| 储存温度 | −20℃ |
| SMILES string | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC |
| InChI | 1S/C22H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h8-9,11-12,14-15,17-18H,3-7,10,13,16,19-21H2,1-2H3/b9-8-,12-11-,15-14-,18-17- |
| InChI key | SNXPWYFWAZVIAU-GKFVBPDJSA-N |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves |
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