1-(2-脱氧-β-<SC>D</SC>-呋喃核糖基）-5-碘尿嘧啶

产品名称：

54-42-2
5-Iodo-2′-deoxyuridine
IDU
IdUrd
2′-Deoxy-5-iodouridine
5-IUdR
1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil
Idoxuridine
5-碘-2′-脱氧尿苷
5-HIAA
碘苷
2′-脱氧-5-碘尿苷
1-(2-脱氧-β-D-呋喃核糖基）-5-碘尿嘧啶

产品介绍：

产品说明

应用

5-Iodo-2′-deoxyuridine has been used in molecular combing assay or DNA fiber assay.
5-碘-2′-脱氧尿苷(5-IUdR；IdUrd)是一种嘧啶类似物(卤代胸苷)，具有抗牛痘病毒(正痘病毒)活性。 IdUrd在人类癌症研究中被用作放射增敏剂。

包装

5, 25 g in glass bottle

生化/生理作用

5-Iodo-2′-deoxyuridine prevents in vitro DNA viral replication. This is observed in herpesviruses and poxviruses It might possess teratogenic, tumor-promoting, mutagenic, and immunosuppressive properties. 5-Iodo-2′-deoxyuridine, used in topical applications, is effective against epithelial infections.

基本信息

经验(实验)分子式	C₉H₁₁IN₂O₅
分子量	354.10
Beilstein	30397
EC 号	200-207-8
MDL编号	MFCD00134656
PubChem化学物质编号	57654307
NACRES	NA.51

产品性质

质量水平	200
测定	≥99% (HPLC)
形式	powder or crystals
mp	194 ℃ (lit.)
溶解性	1 N NH₄OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow
储存温度	2-8℃
SMILES string	OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI	1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI key	XQFRJNBWHJMXHO-RRKCRQDMSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H341 - H361
预防措施声明	P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类	Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges