产品说明
应用
5-Iodo-2′-deoxyuridine has been used in molecular combing assay or DNA fiber assay.
5-碘-2′-脱氧尿苷(5-IUdR；IdUrd)是一种嘧啶类似物(卤代胸苷)，具有抗牛痘病毒(正痘病毒)活性。 IdUrd在人类癌症研究中被用作放射增敏剂。
包装
5, 25 g in glass bottle
生化/生理作用
5-Iodo-2′-deoxyuridine prevents in vitro DNA viral replication. This is observed in herpesviruses and poxviruses It might possess teratogenic, tumor-promoting, mutagenic, and immunosuppressive properties. 5-Iodo-2′-deoxyuridine, used in topical applications, is effective against epithelial infections.
基本信息
| 经验(实验)分子式 | C9H11IN2O5 |
| 分子量 | 354.10 |
| Beilstein | 30397 |
| EC 号 | 200-207-8 |
| MDL编号 | MFCD00134656 |
| PubChem化学物质编号 | 57654307 |
| NACRES | NA.51 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥99% (HPLC) |
| 形式 | powder or crystals |
| mp | 194 ℃ (lit.) |
| 溶解性 | 1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow |
| 储存温度 | 2-8℃ |
| SMILES string | OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O |
| InChI | 1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1 |
| InChI key | XQFRJNBWHJMXHO-RRKCRQDMSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 - H341 - H361 |
| 预防措施声明 | P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| 危险分类 | Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
Sigma-Aldrich
m.cnreagent.com
