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Interferon-αA/D human

品牌
Sigma-Aldrich
货号
I4401
规格纯度
≥95%, recombinant, expressed in E. coli, buffered aqueous solution, suitable for cell culture
参考价格
6647.79 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Interferon-αA/D human
IFN-αA/D
产品介绍:

产品说明

应用

Interferon-αA/D human has been used:

  • for identification of coronavirus replicase inhibitors
  • in combination with ACH-806 [1-(4-pentyloxy-3-trifluoromethylphenyl)-3-(pyridine-3-carbonyl)thiourea] to study the effect on hepatitis C virus (HCV) replication
  • in combination with vitamin D to check reduction in HCV protein production in cell culture

生化/生理作用

Interferon-αA/D (Bg/II), also known as Universal Type I Interferon, is an α interferon hybrid that crosses the species barrier. The Bg/II denotes the restriction enzyme site from which this hybrid is constructed from recombinant human interferons αA and αD. Interferon-αA/D has been proven to be active on many mammalian cells. It can substitute for human, monkey, mouse, bovine, rat, cat, dog, rabbit, sheep, goat, horse, pig or hamster type I interferon (α, β, ω and τ). Type I Interferons are a closely related family of 165-172 amino acid proteins that are produced by leukocytes (α subtypes), fibroblasts (β subtypes), lymphocytes (ω subtypes), and ruminant embryos (τ subtypes). This cytokine has anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities.

外形

Solution in phosphate buffered saline containing 0.1% bovine serum albumin

分析说明

The biological activity is determined in the cytopathic effect inhibition assay using MDBK cells with vesicular stomatitis virus (VSV). A cytopathic effect of 50% is produced with 1 unit/ml interferon. The units are determined with respect to NIH international standard reference for human interferonαA.

基本信息

MDL编号MFCD01635116
NACRESNA.32

产品性质

质量水平200
生物来源human
重组expressed in E. coli
测定≥95%
形式buffered aqueous solution
分子量 19 kDa
包装pkg of 100K units
technique(s)cell culture | mammalian: suitable
杂质 endotoxin, tested
颜色 colorless
UniProt登记号P01563
运输dry ice
储存温度−70℃
Gene Informationhuman ... IFNA2(3440)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves

Sigma-Aldrich

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