Anti-Histone Deacetylase 4 (HDAC4) (ML-19) antibody produced in rabbit

产品名称：

产品介绍：

产品说明

一般描述

Mammalian histone deacetylases (HDACs) can be divided into three classes according to sequence homology. Class II consists of the yeast Hda1-like proteins histone deacetylase 4,5,6,7,8,9, 10 (HDAC4, HDAC5, HDAC6, HDAC7, HDAC9, and HDAC10.

免疫原

synthetic peptide corresponding to amino acid residues 1-19 of human HDAC4 with C-terminal added lysine conjugated to KLH.

应用

Anti-Histone Deacetylase 4 (HDAC4) (ML-19) antibody produced in rabbit has been used in:

immunoblotting
immunoprecipitation
immunofluorescence
immunostaining
immunohistochemistry
chromatin immunoprecipitation

生化/生理作用

Histone deacetylase 4 (HDAC4) exhibits intrinsic nuclear import and export signals for its dynamic nucleocytoplasmic shuttling. Its association with 14-3-3 and monocyte enhancer factor 2 (MEF2) proteins can disturb shuttling and thus directs HDAC4 to the cytoplasm and the nucleus, respectively.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD03791601
NACRES	NA.41

产品性质

生物来源	rabbit
质量水平	200
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen ~140 kDa (additional weaker bands may be present)
species reactivity	rat, mouse, human
technique(s)	immunoprecipitation (IP): 10-20 μg using RIPA extract of HeLa nuclei indirect immunofluorescence: 1:250 using HeLa cells microarray: suitable western blot: 1:1,000 using whole extracts of mouse NIH3T3 cells western blot: 1:500 using whole extracts of rat brain
UniProt登记号	P56524
运输	dry ice
储存温度	−20℃
Gene Information	human ... HDAC4(9759) mouse ... Hdac4(208727) rat ... Hdac4(363287)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable