产品说明
一般描述
Monoclonal Anti-Mad1 (mouse IgG2b isotype) is derived from the hybridoma 9B10 produced by the fusion of mouse myeloma cells (SP2/0 cells) and splenocytes from BALB/c mice immunized with human recombinant Mad1 protein.
Mitotic arrest deficient-like 1 (MAD1) is part of the cell-cycle checkpoint.
免疫原
recombinant human Mad1 protein.
应用
Monoclonal Anti-Mad1 antibody produced in mouse has been used in
生化/生理作用
Mitotic arrest deficient-like 1 (MAD1) functions as a regulator in the segregation of chromosomes during mitosis. It recruits mitotic arrest deficient-like 2 (MAD2) to kinetochores and directs it to function as an inhibitor. MAD1 also helps MAD2 to associate with translocated promoter region (TPr).
外形
Solution in 0.01 M phosphae buffered saline, pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD08705588 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 9B10, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~85 kDa |
| species reactivity | human |
| 浓度 | ~2 mg/mL |
| technique(s) | immunocytochemistry: 10-20 μg/mL using HeLa cells immunoprecipitation (IP): suitable microarray: suitable |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | Q9Y6D9 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MAD1L1(8379) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
