3,5-二甲基-1-碘苯

产品名称：

22445-41-6
1-Iodo-3,5-dimethylbenzene
5-Iodo-m-xylene
3,5-二甲基-1-碘苯
5-碘间二甲苯

产品介绍：

产品说明

一般描述

1-Iodo-3,5-dimethylbenzene (5-Iodo-m-xylene) is an aryl halide. It can be obtained from 5-bromo-m-xylene, via copper-catalyzed halogen exchange reaction, in the presence of NaI or KI in n-BuOH or DMF (solvents). It undergoes reaction with phenol in the presence of CuFe₂O₄nano powder as a recyclable catalyst to afford 1,3-dimethyl-5-phenoxybenzene.

应用

1-Iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is suitable for use in the synthesis of N-(3,5-xylyl)-N-ethylaniline, an arylamine.
It may be used in the following studies:

α-Arylation of ketones.
Copper-catalyzed N-arylation of imidazoles.
Cyanation of 5-iodo-m-xylene to form 3,5-dimethylbenzonitrile.
Synthesis of 1,3-Dimethyl-5-phenoxybenzene by nano-CuFe₂O₄ catalyzed C-O cross-coupling with phenol.
CuBr-catalyzed amination of 1-iodo-3,5-dimethylbenzene to form N-Allyl-3,5-dimethylbenzenamine.
Copper-catalyzed C-S bond-formation between 5-iodo-m-xylene and thiophenol.
As a starting material in the synthesis of biphenyl-3,3′,5,5′-tetracarboxylic acid.
Radical bromination of 5-iodo-m-xylene by N-bromosuccinimide to form 1,3-bis(bromomethyl)-5-iodobenzene.

包装

5, 25 mL in glass bottle

基本信息

线性分子式	(CH₃)₂C₆H₃I
分子量	232.06
MDL编号	MFCD00060659
PubChem化学物质编号	24864461
NACRES	NA.22

产品性质

质量水平	100
测定	99%
折射率	n20/D 1.594 (lit.)
bp	92-94 ℃/3 mmHg (lit.)
密度	1.608 g/mL at 25 ℃ (lit.)
SMILES string	Cc1cc(C)cc(I)c1
InChI	1S/C8H9I/c1-6-3-7(2)5-8(9)4-6/h3-5H,1-2H3
InChI key	ZLMKEENUYIUKKC-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	235.4 °F - closed cup
闪点(C)	113 ℃ - closed cup
个人防护装备	Eyeshields, Gloves, type ABEK (EN14387) respirator filter