1-溴-4-氯-2-氟苯

产品名称：

1996-29-8
1-Bromo-4-chloro-2-fluorobenzene
1-溴-4-氯-2-氟苯

产品介绍：

产品说明

一般描述

1-Bromo-4-chloro-2-fluorobenzene is a polyhalo substituted benzene. It undergoes Suzuki coupling with 2-cyanoarylboronic esters to form the corresponding biphenyls. These biphenyls are the precursors for synthesizing 6-substituted phenanthridines.† The enthalpy of vaporization at boiling point (467.15K) of 1-bromo-4-chloro-2-fluorobenzene is 40.737kjoule/mol.{4}

应用

1-Bromo-4-chloro-2-fluorobenzene may be used in the preparation of benzonorbornadiene derivative. It may also be used as a starting material in the multi-step synthesis of AZD3264, an IKK2 (inhibitor of nuclear factor κ-B kinase-2) inhibitor.

包装

25 g in glass bottle

基本信息

线性分子式	BrC₆H₃(Cl)F
分子量	209.44
MDL编号	MFCD00079708
PubChem化学物质编号	24877906
NACRES	NA.22

产品性质

质量水平	200
测定	98%
折射率	n20/D 1.556 (lit.)
bp	91-92 ℃/20 mmHg (lit.)
密度	1.678 g/mL at 25 ℃ (lit.)
SMILES string	Fc1cc(Cl)ccc1Br
InChI	1S/C6H3BrClF/c7-5-2-1-4(8)3-6(5)9/h1-3H
InChI key	FPNVMCMDWZNTEU-UHFFFAOYSA-N

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	198.0 °F - closed cup
闪点(C)	92.2 ℃ - closed cup
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)