产品说明
一般描述
Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-myc gene encodes for a protein of 62kDa called p62c-myc is associated mainly with cell nuclei.
免疫原
人p62c-Myc蛋白的合成肽。
应用
Monoclonal Anti-c-Myc-Alkaline Phosphatase antibody can be used for western blot assays at 1:100, using myc-tagged fusion proteins. The antibody can also be used for immunohistochemical applications.
Anti-c-Myc-Alkaline Phosphatase antibody has been used in
生化/生理作用
The c-myc oncogene product(p62c-myc) exerts normal and oncogenic cellular functions. Elevated level of c-myc protein in malignant tissues when compared with normal tissue, but with the unexpected finding of a cytoplasmic accumulation of the protein in these tumors.
外形
Solution in 0.05 M Tris buffer, containing 1% bovine serum albumin, 1 mM MgCl2, 50% glycerol, and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
质量水平 | 200 |
生物来源 | mouse |
偶联物 | alkaline phosphatase conjugate |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 9E10, monoclonal |
形式 | buffered aqueous glycerol solution |
species reactivity | human |
technique(s) | ELISA: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable western blot: 1:100 using a myc-tagged fusion protein. |
同位素/亚型 | IgG1 |
UniProt登记号 | P01106 |
储存温度 | 2-8℃ |
Gene Information | human ... MYC(4609) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich