产品说明
一般描述
CD13 (aminopeptidase-N) is a transmembrane protease present in many tissues and cell types (e.g., endothelial and epithelial cells, fibroblasts, and leukocytes). CD13 is expressed in various solid and hematological malignancies in humans and is useful in identifying acute myeloid leukemia when used in a panel including antibodies against CD13(+), CD34(+), CD117(+), CD16(-), and CD33(+). This protein is also expressed in myeloid sarcoma and anti-CD13 is useful in its identification using a panel.
In addition, it has been reported that CD13 is expressed in both normal and neoplastic liver tissue, where it exhibits a canalicular distribution pattern similar to that seen for polyclonal CEA and CD10. Thus, anti-CD13 can be useful as an additional marker in differentiating between HCC and non-hepatocellular neoplasms.
质量
United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO
联系
CD13 Positive Control Slides, Product No. 113S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外形
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
制备说明
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其他说明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律信息
Cell Marque is a trademark of sigma-aldrich Co. LLC
产品性质
| 质量水平 | 500 100 |
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | EP117, monoclonal |
| 描述 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 包装 | vial of 0.1 mL concentrate (113R-24) vial of 0.1 mL concentrate Research Use Only (113R-24-RUO) vial of 0.5 mL concentrate (113R-25) vial of 1.0 mL concentrate (113R-26) vial of 1.0 mL concentrate Research Use Only (113R-26-RUO) vial of 1.0 mL pre-dilute Research Use Only (113R-27-RUO) vial of 1.0 mL pre-dilute ready-to-use (113R-27) vial of 7.0 mL pre-dilute ready-to-use (113R-28) vial of 7.0 mL pre-dilute ready-to-use Research Use Only (113R-28-RUO) |
| manufacturer/tradename | Cell Marque™ |
| 浓度 | 0.1-5 μg/mL (predilute) 2.5-125 μg/mL (concentrate) |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated) |
| 同位素/亚型 | IgG |
| 控制 | liver |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| 可视化 | cytoplasmic, membranous |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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