产品说明
一般描述
Mouse monoclonal anti-phospho-ATF-2 (pThr69,71) reacts specifically with ATF2 phosphorylated at both threonine 69 and 71, and does not detect the monophosphorylated and the non-phosphorylated ATF2 molecule. The epitope recognized by the antibody resides in the N-terminal region of ATF2 (aa 66-79, pT69,71). This epitope is identical in ATF2 of human, rat, mouse, chicken and frog. The antibody cross-reacts with human, rat and mouse ATF2.
ATF2 (Activating Transcription Factor 2) is a member of the leucine zipper family of transcription factors. It binds to CRE domains and stimulates CRE-dependent transcription.
免疫原
synthetic peptide corresponding to the N-terminal amino acids 66-79 (pT69,71) of human ATF2. This sequence is identical in ATF2 from human, rat, mouse, chicken, and frog.
应用
Mouse monoclonal anti-phospho-ATF-2 (pThr69,71) antibody can be used for immunocytochemistry, indirect ELISA, microarray, and western blot.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.
制备说明
Purified from culture supernatant of hybridoma cells grown in a bioreactor.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD03096614 |
NACRES | NA.41 |
产品性质
质量水平 | 200 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | ATF-22P, monoclonal |
形式 | buffered aqueous solution |
分子量 | antigen 60-70 kDa (triplet) |
species reactivity | frog, rat, mouse, chicken, human |
浓度 | 0.5-1.0 mg/mL |
technique(s) | immunocytochemistry: suitable indirect ELISA: suitable microarray: suitable western blot: suitable |
同位素/亚型 | IgG1 |
UniProt登记号 | P15336 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... ATF2(1386) mouse ... Atf2(11909) rat ... Atf2(81647) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich