产品说明
一般描述
Interleukin-1α (IL-1α) is a cytokine that belongs to the interleukin-1 (IL-1) family. It is located intracellularly in hematopoietic and non-hematopoietic cells. IL-1α gene is located on the human chromosome at 2q14.1.
应用
Interleukin-1α (IL-1α) has been used:
包装
2 μg in serum bottle
生化/生理作用
Interleukin-1α (IL-1α) plays a crucial role in inflammation during cell necrosis. It also regulates the recruitment of interleukin-1β (IL-1β), neutrophils, chemokines, and other cytokines at the site of injury. IL-1α exhibits a dual function of binding to its cell surface receptor as well as chromatin.
外形
Lyophilized from 0.2 μm filtered 10 mM sodium phosphate , pH 8.0, plus 50 mm NaCl and 50 μg bovine serum albumin (BSA) per μg cytokine.
分析说明
The proliferative activity of human IL-1α is tested in culture using the murine cell line D10S.
基本信息
| MDL编号 | MFCD00164814 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥98% (SDS-PAGE and HPLC) |
| 形式 | lyophilized powder |
| 质量 | endotoxin tested |
| 分子量 | ~17 kDa |
| 包装 | pkg of 2 and 10 μg |
| technique(s) | cell culture | mammalian: suitable |
| UniProt登记号 | P01583 |
| 储存温度 | −20℃ |
| Gene Information | human ... IL1A(3552) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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