<sc>L</sc>-<i>trans</i>-Pyrrolidine-2,4-dicarboxylic acid

产品名称：

64769-66-0
L-trans-Pyrrolidine-2,4-dicarboxylic acid
L-trans-2,4-PDC
(2S,4R)-Pyrrolidine-2,4-Dicarboxylic Acid
trans-4-Carboxy-L-proline

产品介绍：

产品说明

应用

L-trans-Pyrrolidine-2,4-dicarboxylic acid has been used:

as a glutamate transport inhibitor to test its impairing effect on glutamate-induced cell death in HT22 neuronal cells
as an analog of glutamate to test its effect on glutamate/glutamine-dependent acid resistance of E. coli and S. flexneri
as sodium glutamate (Na⁺/Glu) cotransporter inhibitor in myogenic cell line C2C12

包装

2, 10 mg in glass insert

生化/生理作用

L-trans-Pyrrolidine-2,4-dicarboxylic acid is a selective glutamate transporter inhibitor.

基本信息

产品性质

质量水平	100
测定	≥98%
SMILES string	OC(=O)[C@H]1CN[C@@H](C1)C(O)=O
InChI	1S/C6H9NO4/c8-5(9)3-1-4(6(10)11)7-2-3/h3-4,7H,1-2H2,(H,8,9)(H,10,11)/t3-,4+/m1/s1
InChI key	NRSBQSJHFYZIPH-DMTCNVIQSA-N
Gene Information	rat ... Gria1(50592), Grik1(29559), Grin2a(24409), Slc1a2(29482), Slc1a3(29483)

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

L-trans-Pyrrolidine-2,4-dicarboxylic acid