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位置:首页 > 品牌 > Sigma-Aldrich > Monoclonal Anti-Rat Kappa Light Chains (1a + 1b) antibody produced in mouse

Monoclonal Anti-Rat Kappa Light Chains (1a + 1b) antibody produced in mouse

品牌
Sigma-Aldrich
货号
R9010
规格纯度
clone RT-39, ascites fluid
参考价格
4729.39 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-Rat Kappa Light Chains (1a + 1b) antibody produced in mouse
Monoclonal Anti-Rat Kappa Light Chains (1a + 1b)
产品介绍:

产品说明

一般描述

Monoclonal anti-Rat Light Chain (1a+1b) (mouse IgG1 isotype) is derived from the RT-39 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified rat IgG. An immunoglobulin (Ig) has two heavy chain and two light chain connected by disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. Rat has five immunoglobulin classes- IgM, IgG, IgA, IgD and IgGE. IgG has four subclasses- IgG1, IgG2a, IgG2b and IgG2c. Rat immunoglobulins have either κ or λ light chains. Greater than 90% of normal rat immunoglobulins and myelomas contain light chains.

特异性

The antibody reacts with an epitope on the rat κ light chain, which is shared by both the 1a and 1b allotypes in various rat immunoglobulin classes and subclasses. No cross-reactivity is observed with rat λ light chains or with IgG from human, mouse, bovine, rabbit, goat, sheep, horse, dog, chicken, pig or cat. The product shows weak cross-reaction with guinea pig IgG.

免疫原

Purified rat IgG

应用

Monoclonal Anti-Rat κ Light Chains (1a + 1b) antibody has been used in capture enzyme linked immunosorbent assay (ELISA), immunoblotting, dot blot and immunocytochemistry.
Monoclonal Anti-Rat Kappa Light Chains (1a + 1b) antibody produced in mouse has been used in:

  • enzyme-linked immunosorbent assay (ELISA)
  • immunoblotting
  • dot blot
  • immunocytochemistry

生化/生理作用

Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III reactions. It helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00164734
NACRESNA.46

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式ascites fluid
antibody product typesecondary antibodies
克隆RT-39, monoclonal
分子量antigen 25 kDa
包含15 mM sodium azide
technique(s)capture ELISA: suitable
dot blot: suitable
immunocytochemistry: suitable
indirect ELISA: 1:2,000
western blot: suitable using denatured and reduced normal serum or myeloma protein
同位素/亚型IgG1
运输dry ice
储存温度−20℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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