Anti-Human IgE-Alkaline Phosphatase antibody, Mouse monoclonal

产品说明

一般描述

IgEs are glycoprotein antibodies that regulate immunological responses to allergies and infections. These immunoglobulins have been implicated in mediating Type I hypersensitivity reactions. Elevated IgE levels have been associated with hyper IgE syndrome and allergic asthma.
Monoclonal Anti-Human IgE (mouse IgG2b isotype) is derived from the GE-1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
Binds human IgE; does not bind human IgG, IgA or IgM.

应用

Mouse monoclonal anti-human IgE-alkaline phosphatase antibody has been used for :

• immunoblot assays
• direct ELISA
• dot blot

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
To confirm that a chimaeric monoclonal antibody had episolon chain, an elisa was performed using monoclonal anti-human IgE antibody (clone GE1) at a 1:1000 dilution.

生化/生理作用

IgEs are glycoprotein antibodies that regulate immunological responses to allergies and infections. These immunoglobulins have been implicated in mediating Type I hypersensitivity reactions. Elevated IgE levels have been associated with hyper IgE syndrome and allergic asthma.

外形

Solution in 0.05 M Tris, pH 8.0, containing 1% bovine serum albumin, 1 mM MgCl₂ and 15 mM sodium azide

分析说明

The antibody is tested for reactivity against myeloma IgE and allergy-elevated IgE.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.46

产品性质

质量水平	200
生物来源	mouse
偶联物	alkaline phosphatase conjugate
抗体形式	purified from hybridoma cell culture
antibody product type	secondary antibodies
克隆	GE-1, monoclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	direct ELISA: 1:6,000 dot blot: 1:1,000
同位素/亚型	IgG2b
运输	wet ice
储存温度	2-8℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)