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Monoclonal Anti-Neural Cell Adhesion Molecule antibody produced in mouse

品牌
Sigma-Aldrich
货号
C9672
规格纯度
clone NCAM-0B11, ascites fluid
参考价格
5149.17 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-Neural Cell Adhesion Molecule antibody produced in mouse
Anti-NCAM
Anti-CD56-CY
产品介绍:

产品说明

一般描述

Monoclonal Anti-N-CAM (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Neural cell adhesion molecule (N-CAM), the best characterized CAM, exists in adult brain. It belongs to the family of sialoglycoproteins, which arise from alternative splicing of mRNA transcribed from a single gene. Immunocytochemical data indicate that in the adult, N-CAM is expressed mainly in cells of the nervous system. There are indications that N-CAM may also be expressed by non-neural cells in the adult, as it has been found in studies of various embryonic developmental stages.
Mouse monoclonal clone NCAM-0B11 anti-Neural Cell Adhesion Molecule antibody localizes the high molecular weight isoform of N-CAM (neural cell adhesion molecule) in human and several other mammalian species. The antibody shows a strong reaction to N-CAM A/N-CAM 180, however it also recognizes N-CAM B/N-CAM 140. In an immunoblot, the product reacts with polysialated N-CAM in embryonic material. Breakdown products of N-CAM may be stained; they appear as bands lower than 100 kD on the immunoblot.

免疫原

growth cone enriched plasma membrane fraction from E17 rat forebrain.

应用

Monoclonal Anti-Neural Cell Adhesion Molecule antibody produced in mouse has been used in:

  • Immunofluorescence
  • Immunohistochemistry
  • Immunoblotting


Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (3 papers)

生化/生理作用

Neural cell adhesion molecule (N-CAM) are believed to be involved in cell-cell interactions and probably play an important role in embryogenesis and development.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00164707
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆NCAM-0B11, monoclonal
分子量antigen 140-180 kDa
包含15 mM sodium azide
species reactivityrat, human
technique(s)immunocytochemistry: suitable using cells and tissues
western blot: 1:100 using a freshly prepared extract from newborn and adult rat brain, or rat cerebral cortex extract
同位素/亚型IgG1
UniProt登记号O15394
P13591
运输dry ice
储存温度−20℃
Gene Informationhuman ... NCAM1(4684), NCAM2(4685)
rat ... Ncam1(24586), Ncam2(288280)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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