三氟甲烷磺酸酐

产品名称：

358-23-6
Trifluoromethanesulfonic Anhydride
Tf₂O
Triflic anhydride
三氟甲磺酸酐
三氟甲烷磺酸酐

产品介绍：

产品说明

应用

Trifluoromethanesulfonic anhydride can be used in the preparation of azido sugars such as 6-azido fucose. It can also be used as a promoter for the Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the absence of catalyst.
Tf2O in combination with:

Diphenyl sulfoxide, forms an efficient promoter system for the activation of thioglycosides for glycosylation reactions.
2-chloropyridine, can be used for secondary amide activation.
Potassium iodide, can effectively mediate the deoxygenation of sulfoxides to form sulfides.
Hydrogen peroxide, for the selective oxidation of sulfanes to sulfoxides in the presence of oxidatively sensitive functional groups.

Tf2O can react with:

Ketones in the presence of a base to form vinyl triflates.
Magnesium alkoxides to form corresponding symmetrical or unsymmetrical ethers.
Sodium azide for the in situ preparation of triflyl azide.

糖基化合成催化剂糖基化合成试剂
甘露三嗪甲基脲酸酯供体糖基化空间选择性合成试剂
异丙基羟基糖直接糖基化活化剂

包装

100 mL in glass bottle

其他说明

亲电子三氟甲磺酰基的来源。综述

基本信息

线性分子式	(CF₃SO₂)₂O
分子量	282.14
Beilstein	1813600
EC 号	206-616-8
MDL编号	MFCD00000408
PubChem化学物质编号	329770073
NACRES	NA.22

产品性质

质量水平	200
蒸汽密度	5.2 (vs air)
蒸汽压	8 mmHg ( 20 ℃)
等级	purum
测定	≥98.0% (T)
形式	liquid
折射率	n20/D 1.321 (lit.)
bp	81-83 ℃ (lit.)
密度	1.677 g/mL at 25 ℃ (lit.)
SMILES string	FC(F)(F)S(=O)(=O)OS(=O)(=O)C(F)(F)F
InChI	1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8
InChI key	WJKHJLXJJJATHN-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H272 - H302 - H314 - H335
预防措施声明	P210 - P220 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Dam. 1 - Ox. Liq. 2 - Skin Corr. 1B - STOT SE 3
靶器官	Respiratory system
补充剂危害	EUH014
储存分类代码	5.1B - Oxidizing hazardous materials
WGK	WGK 3
个人防护装备	Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter