产品说明
包装
10, 25, 50 mg in poly bottle
生化/生理作用
A diadenosine polyphosphate stored in secretory granules of thrombocytes, chromaffin and neuronal cells. After release into the extracellular space, it affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5′-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. In heart, it increases contractile force and action potential duration, and shows an anti-β-adrenergic effect.
基本信息
经验(实验)分子式 | C20H29N10O22P5 · xNH3 · yH2O |
分子量 | 916.37 (anhydrous free acid basis) |
eCl@ss | 32160414 |
PubChem化学物质编号 | 24894177 |
NACRES | NA.77 |
产品性质
质量水平 | 200 |
生物来源 | synthetic (organic) |
测定 | ≥95% (HPLC) |
形式 | powder |
颜色 | white to off-white |
溶解性 | H2O: 50 mg/mL |
储存温度 | −20℃ |
SMILES string | O[C@@H]1[C@@H](COP(OP(O)(OP(O)(OP(O)(OP(O)(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N(C=N3)C4=C3C(N)=NC=N4)O2)=O)=O)=O)=O)(O)=O)O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@@H]1O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich