产品说明
一般描述
PHLPP1 is the protein phosphatase responsible for dephosphorylation of the Akt (Ser473) site. Akt (Ser473) is the TORC2 (mTOR) phosphorylation activation site.
特异性
This antibody recognizes the C-terminal region of PHLPP1.
免疫原
KLH-conjugated linear peptide corresponding to the C-terminus of PHLPP1.
Epitope: C-terminus
应用
Research Category
Signaling
Anti-PHLPP1 Antibody detects level of PHLPP1 & has been published & validated for use in WB & IC.
Research Sub Category
PI3K, Akt, & mTOR Signaling
质量
Evaluated by Western Blot in Human brain tissue lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected PHLPP1 in Human brain tissue lysate.
目标描述
134 kDa Observed at 110 kDa
外形
Purified rabbit serum in buffer containing 0.1 M Tris-glycine, pH 7.4, 150 mM NaCl and 0.05% sodium azide.
Affinity purified
储存及稳定性
Maintain refrigerated at 2-8°C for 1 year from date of receipt.
分析说明
Control
Human brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse, rat, human |
technique(s) | immunocytochemistry: suitable western blot: suitable |
NCBI登记号 | NP_919431 |
UniProt登记号 | O60346 |
运输 | wet ice |
Gene Information | human ... PHLPP1(23239) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich