产品说明
应用
Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) has been used as a caspase inhibitor to study its effects on lactate dehydrogenase (LDH) leakage, apoptosis and virus proliferation in chorion cells , as a component of the transplantation medium for the transplantation of human embryonic stem cells (ESC)-derived medial ganglionic eminence (MGE) cells into hippocampus of mice , as a protease inhibitor to study its effects on cell death in parasites .
包装
3 mg in glass bottle
生化/生理作用
Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) permits cell permeability. It is a caspase inhibitor and suppresses apoptosis induced by various kinds of stimuli. Boc-D-fmk poorly inhibits caspases-2, -5, -6 and -10.
基本信息
| 经验(实验)分子式 | C11H18NO5F |
| 分子量 | 263.26 |
| MDL编号 | MFCD03453073 |
| PubChem化学物质编号 | 329773206 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥90% (TLC) |
| 形式 | solid |
| 溶解性 | DMF: soluble |
| 储存温度 | −20℃ |
| SMILES string | COC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)CF |
| InChI | 1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)/t7-/m0/s1 |
| InChI key | MXOOUCRHWJYCAL-ZETCQYMHSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
