产品说明
一般描述
Anti-NMDAR1 antibody detects endogenous levels of total NMDAR1 protein.
N-methyl-d-aspartate receptor (NMDAR1) is a subtype of the ionotropic glutamate receptors (iGluRs). It is coded by GRIN1 gene. It is located on human chromosome 9q34.3. NMDAR1is expressed in epidermal melanocytes.
免疫原
The antiserum was produced against synthesized peptide derived from human NMDAR1.
Immunogen Range: 856-905
应用
Anti-NMDAR1, C-Terminal antibody has been used in western blot analysis.
生化/生理作用
N-methyl-d-aspartate receptor (NMDAR1) plays an important role in the pathophysiology of schizophrenia, bipolar disorder and depression. Mutations in GRIN1 gene results in severe intellectual disability, hypotonia, hyperkinetic and stereotyped movements, and epilepsy.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 105 kDa |
| species reactivity | rat, mouse, human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI登记号 | Q05586 |
| UniProt登记号 | Q05586 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GRIN1(2902) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
