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位置:首页 > 品牌 > Sigma-Aldrich > Monoclonal Anti-Nicotinic Acetylcholine Receptor (α7 Subunit) antibody produced in mouse

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α7 Subunit) antibody produced in mouse

品牌
Sigma-Aldrich
货号
M220
规格纯度
~5 mg/mL, clone mAb 306, purified immunoglobulin, buffered aqueous solution
参考价格
8359.4 *本价格含增值税费
促销
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数量
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产品名称:
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α7 Subunit) antibody produced in mouse
产品介绍:

产品说明

一般描述

Nicotinic acetylcholine receptors (nAChRs) function as ligand-gated channels that modulate endoplasmic reticulum stress and neurotransmitter release. These receptors also control synaptic signaling in ganglia and muscles. The α7 form of nAChR is expressed in mitochondria and regulates Ca2+ transport and the release of cytochrome c. When expressed in non-excitable cells, α7 nAChR mediates cell growth and survival
Monoclonal anti-nicotinic acetylcholine receptor ((α7) subunit) antibody is specific for native and denatured α7 subunits in chick, as well as for the denatured α7 subunits in rats and humans. The antibody does not bind well to the native form of the mammalian α7 subunit. The product can be used in chick, rat and human tissues.

免疫原

native and denatured α7 subunit (amino acids 380-400, binds α-bungarotoxin) of the nicotinic acetylcholine receptor from chicken and the denatured α7 subunit from rat.

应用

Monoclonal anti-nicotinic acetylcholine receptor ((α7) subunit) antibody is suitable for use in immunocytochemistry (at 1:3000-1:50 dilutions using paraformaldehyde fixed, cultured rat chromaffin cells) , and immunohistochemistry (at 1:3,000 dilutions using frozen sections).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

外形

Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.

法律信息

Sold with permission of the Salk Institute

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00677279

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆mAb 306, monoclonal
形式buffered aqueous solution
species reactivityhuman (denatured), rat (denatured), chicken
浓度~5 mg/mL
technique(s)immunohistochemistry (frozen sections): 1:3,000
同位素/亚型IgG1
UniProt登记号P36544
运输dry ice
储存温度−20℃
Gene Informationhuman ... CHRNA7(1139)
rat ... Chrna7(25302)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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