Anti-Endothelin Receptor B antibody produced in rabbit

产品说明

一般描述

Endothelin Receptor B (EDNRB) is a G-protein coupled receptor and that consists of seven transmembrane domains. EDNRB gene is located on the human chromosome at 13q22.3.

免疫原

synthetic peptide corresponding to amino acids 298-313 of rat endothelin receptor type B. The epitope is identical in all known vertebrate ET-B receptors

应用

Anti-Endothelin Receptor B antibody produced in rabbit has been used in immunohistochemistry (1:100).

生化/生理作用

EDNRB Endothelin receptor type B (ETB) plays a pivotal role in oesophageal cancer and may act as a therapeutic target for this intractable malignancy. It has a novel role in oligodendroglioma proliferation and acts as a potential therapeutic alternative for oligodendrogliomas. Lower expression of ETB receptor responsiveness is associated with polycystic ovary syndrome (PCOS) and may reflect lower endothelial-mediated vasodilatation independent of generally lower vascular reactivity.
Mutations in the EDNRB gene are associated with Hirschsprung disease.

外形

Lyophilized at 0.8 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335 - H412
预防措施声明	P273 - P302 + P352 - P305 + P351 + P338
危险分类	Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable