产品说明
一般描述
6-(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose)polymerase (PARP)-1 activity. The ability of 6-(5H)-phenanthridinone to potentiate the effect of ionizing radiation on tumour cells was evaluated. Action of 6-(5H)-phenanthridinone, one of the most potent PARP inhibitor, on RDM4 murine lymphoma cells in culture was evaluated.
应用
Reactant involved in:
包装
1 g in glass bottle
基本信息
经验(实验)分子式 | C13H9NO |
分子量 | 195.22 |
EC 号 | 213-804-3 |
MDL编号 | MFCD00004988 |
PubChem化学物质编号 | 24858050 |
NACRES | NA.22 |
产品性质
等级 | technical grade |
质量水平 | 100 |
mp | 290-292 ℃ (lit.) |
SMILES string | O=C1Nc2ccccc2-c3ccccc13 |
InChI | 1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15) |
InChI key | RZFVLEJOHSLEFR-UHFFFAOYSA-N |
Gene Information | human ... PARP1(142) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich