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位置:首页 > 品牌 > Sigma-Aldrich > 6-(5H)-菲啶酮

6-(5H)-Phenanthridinone

6-(5H)-菲啶酮

品牌
Sigma-Aldrich
CAS
1015-89-0
货号
299634
包装型号
规格纯度
technical grade
参考价格
308.6 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
1015-89-0
6-(5H)-Phenanthridinone
NSC 11021
NSC 40943
NSC 61083
6-(5H)-菲啶酮
产品介绍:

产品说明

一般描述

6-(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose)polymerase (PARP)-1 activity. The ability of 6-(5H)-phenanthridinone to potentiate the effect of ionizing radiation on tumour cells was evaluated. Action of 6-(5H)-phenanthridinone, one of the most potent PARP inhibitor, on RDM4 murine lymphoma cells in culture was evaluated.

应用

Reactant involved in:

  • Synthesis of 5,6-dihydrophenanthridine sulfonamides
  • Oxidative coupling with diphenylacetylene
  • Direct copper acetate-catalyzed N-cyclopropylation of cyclic amides

Reactant involved in the synthesis and/or pharmacological activity of biologically active molecules including:
  • Potassium channel KV1.3 and IK-1 inhibitors
  • HIV-1 integrase inhibitors

包装

1 g in glass bottle

基本信息

经验(实验)分子式C13H9NO
分子量195.22
EC 号213-804-3
MDL编号MFCD00004988
PubChem化学物质编号24858050
NACRESNA.22

产品性质

等级technical grade
质量水平100
mp290-292 ℃ (lit.)
SMILES stringO=C1Nc2ccccc2-c3ccccc13
InChI1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15)
InChI keyRZFVLEJOHSLEFR-UHFFFAOYSA-N
Gene Informationhuman ... PARP1(142)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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