产品说明
一般描述
CD73, also known as Ecto-5′-nucleotidase, catalyzes the conversion of purine 5′ mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation, being expressed on subsets of B-cells and T-cells. CD73 is also a marker of undifferentiated mesenchymal stem cells and is often used to identified stem cell populations.
免疫原
Whole Mouse Dermal Lymphatic Endothelial Cells (DLEC)
应用
Research Sub Category
Mesenchymal Stem Cells
Evaluated by Immunocytochemistry on human bone marrow mesenchymal stem cells. Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.
Research Category
Stem Cell Research
This Anti-CD73, clone AA60-E3-3 is validated for use in Immunocytochemistry for the detection of CD73.
质量
Evaluated by Immunocytochemistry on human adipose mesenchymal stem cells.
Immunocytochemical analysis: A 1:50 dilutions of this antibody detected CD73 on 1X10^6 human adipose and bone marrow mesenchymal stem cells.
目标描述
The unconjugated parent antibody (Catalog No. MABD122) has an observed MW at 63 kDa
外形
Purified mouse monoclonal IgG1κ conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.
Protein G Purified
储存及稳定性
Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
法律信息
ALEXA FLUOR is a registered trademark of Life Technologies
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.44 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | ALEXA FLUOR® 488 |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | AA60-E3-3, monoclonal |
species reactivity | human |
species reactivity (predicted by homology) | mouse (immunogen homology) |
technique(s) | immunocytochemistry: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_001191742 |
UniProt登记号 | Q61503 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich