Anti-phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor^® 488

产品说明

一般描述

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

特异性

Broad species cross-reactivity is expected.
Histone H3 phosphorylated at Ser10

免疫原

Epitope: Ser10
A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3.

应用

Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Alexa Fluor^® 488, is a Mouse Monoclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p,
is labeled with Alexa Fluor 488 and validated for use in FC.
Research Category
Epigenetics & Nuclear Function

Apoptosis & Cancer
Research Sub Category
Histones

Cell Cycle, DNA Replication & Repair

质量

Evaluated by Flow Cytometry with Jurkat cells.

目标描述

17 kDa observed

外形

Purified mouse IgG1k conjugated to Alexa Fluor^® 488 in PBS with 15mg/mL BSA and less than 0.09% sodium azide.
Protein G Purified

储存及稳定性

Maintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light.

分析说明

Control
Jurkat Cells

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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