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Anti-SC-35 Antibody, clone 1SC-4F11

品牌
Sigma-Aldrich
货号
04-1550
规格纯度
ascites fluid, clone 1SC-4F11, from mouse
参考价格
5697.8 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
Anti-SC-35 Antibody, clone 1SC-4F11
Protein PR264, Splicing component, 35 kDa, Splicing factor SC35, splicing factor, arginine/serine-rich 2
产品介绍:

产品说明

一般描述

SC-35 is also known as Splicing factor SC35 and Splicing factor, arginine/serine-rich 2. This protein is encoded by the SFRS2 gene and is a member of the splicing factor SR family. SC-35 is involved in pre-mRNA splicing and is found in bodies in the nucleus that are highly enriched in poly(A) RNA. These nuclear bodies are referred to as speckles, SC 35 domains, or splicing factor compartments (SFCs). The purpose of these bodies is still widely disputed. Speckles correspond largely to, if not entirely to, ultra structures called inter-chromatin granule clusters (IGCs). SC3-35 is required for pre-mRNA splicing events and is highly involved in spliceosomal interaction and assembly. SC-35 is necessary for assembly of the ATP-dependent splicing complex. It is also necessary for the ATP-dependent communication between pre-mRNA and U1 and U2 snRNPs.

特异性

This antibody recognizes SC35.

免疫原

Epitope: Unknown
Ovalbumin-conjugated linear peptide corresponding to human SC35.

应用

Research Category
Epigenetics & Nuclear Function
Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected SC35 in NIH/3T3 cells.
Anti-SC-35 Antibody, clone 1SC-4F11 is a Mouse Monoclonal Antibody for detection of SC-35 also known as Protein PR264, Splicing factor SC35 & has been validated in WB, ICC.
Research Sub Category
RNA Metabolism & Binding Proteins

质量

Evaluated by Western Blot in A431 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected Sc35 on 10 µg of A431 cell lysate.

目标描述

~ 35 kDa

外形

Unpurified
Unpurified mouse monoclonal IgG1κ preservative-free ascites.

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
A431 cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆1SC-4F11, monoclonal
species reactivitymouse, human, rat
technique(s)immunocytochemistry: suitable
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_003007.2
UniProt登记号Q01130
运输dry ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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