双[3-羧基吡啶] 6,6′-二硫化物

产品名称：

15658-35-2
6,6′-Dithiodinicotinic acid
Bis[3-carboxypyridine] 6,6′-disulfide
6,6′-二硫二烟酸
双[3-羧基吡啶] 6,6′-二硫化物
双[3-羧基吡啶] 6,6′-二硫醚

产品介绍：

产品说明

一般描述

6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported.

应用

6,6′-Dithiodinicotinic acid may be employed as:

specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
spectrophotometric determination of thiols and of total glutathione in human blood

包装

5 g in glass bottle

基本信息

经验(实验)分子式	C₁₂H₈N₂O₄S₂
分子量	308.33
EC 号	239-729-6
MDL编号	MFCD00006454
PubChem化学物质编号	24863248
NACRES	NA.22

产品性质

等级	technical grade
测定	85%
mp	263-265 ℃ (lit.)
SMILES string	OC(=O)c1ccc(SSc2ccc(cn2)C(O)=O)nc1
InChI	1S/C12H8N2O4S2/c15-11(16)7-1-3-9(13-5-7)19-20-10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)
InChI key	GSASOFRDSIKDSN-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves