产品说明
一般描述
Methyl isonipecotate can be obtained by the reduction of methyl isonicotinate in methanol with ruthenium at 100-150℃.
应用
Methyl isonipecotate may be used for the synthesis of a series of potent non-urea soluble epoxide hydrolase (sEH) inhibitors via high throughput screens.
Precipitate may form upon standing which should not affect application.
Reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation
Reactant for synthesis of:
Antitubercular agents
Anti-HIV-1 agents
Aminopyrazine inhibitors
Orally available naphthyridine protein kinase D inhibitors
A Scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide
包装
25, 100 mL in glass bottle
基本信息
| 经验(实验)分子式 | C7H13NO2 |
| 分子量 | 143.18 |
| MDL编号 | MFCD00190578 |
| PubChem化学物质编号 | 24870073 |
| NACRES | NA.22 |
产品性质
| 等级 | technical grade |
| 质量水平 | 100 |
| 折射率 | n |
| bp | 85-90 ℃ (lit.) |
| 密度 | 1.06 g/mL at 25 ℃ (lit.) |
| SMILES string | COC(=O)C1CCNCC1 |
| InChI | 1S/C7H13NO2/c1-10-7(9)6-2-4-8-5-3-6/h6,8H,2-5H2,1H3 |
| InChI key | RZVWBASHHLFBJF-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | 192.2 °F - closed cup |
| 闪点(C) | 89 ℃ - closed cup |
| 个人防护装备 | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
Sigma-Aldrich
m.cnreagent.com
