产品说明
一般描述
An endogenous lipid that acts as a selective agonist for GPR55 receptors (EC50 = 4, 19 800 and >30 000 nM at GPR55, CB2 and CB1 receptors respectively). Producing robust anti-inflammatory actions by activating PPARα (EC50 = 3 µM).
生化/生理作用
Primary Target
GPR55 receptor
警告
Toxicity: Standard Handling (A)
制备说明
Slight warming is required for complete solubilization.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Griffin, G., et al. 2000. J. Pharmacol. Exp. Ther.292, 886.
Lambert, D., et al. 2001. Epilepsia.42, 321.
Lambert, D., et al. 2002. Curr. Med. Chem.9, 663.
Lo Verme, J., et al. 2005. Life Sci.77, 1685.
Re, G., et al. 2005. Vet. J.173, 21.
Ryberg, R., et al. 2007. Br. J. Pharmacol.152, 1092.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C18H37NO2 |
| 分子量 | 299.49 |
| MDL编号 | MFCD00020562 |
产品性质
| 测定 | ≥99% (HPLC) |
| 质量水平 | 100 |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze protect from light |
| 颜色 | white |
| 溶解性 | DMSO: 20 mM |
| 储存温度 | −20℃ |
| InChI | 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21) |
| InChI key | HXYVTAGFYLMHSO-UHFFFAOYSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H315 - H318 - H411 |
| 预防措施声明 | P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 |
| 危险分类 | Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
