CL-82198-CAS 1188890-36-9-Calbiochem

产品说明

一般描述

A selective inhibitor of MMP-13 (IC₅₀ = 10 µM) that does not appear to act by chelating Zn²⁺. Binds within the entire S1′ pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.
A selective inhibitor of MMP-13 (IC₅₀ = 10 µM). Binds to the S1′ pocket of MMP-13 with its morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.

包装

5 mg in Plastic ampoule

生化/生理作用

Target IC₅₀: 10 µM against MMP-13
Product does not compete with ATP.
Reversible: no
Primary Target
MMP-13
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

其他说明

Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

产品性质

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