NS 2028-CAS 204326-43-2-Calbiochem

产品说明

一般描述

Potent, specific, and irreversible inhibitor of soluble guanylyl cyclase (IC₅₀ = 30 nM for basal and 200 nM for NO-stimulated enzyme activity; IC₅₀ = 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum).

包装

5 mg in Plastic ampoule

生化/生理作用

Primary Target
basal soluble guanylyl cyclase
Target IC₅₀: 30 nM for basal and 200 nM for NO-stimulated enzyme activity; 17 nM for S-nitrosoglutathione-enhanced soluble guanylyl cyclase activity in homogenates of mouse cerebellum
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C) for long-term storage. DMSO stock solutions are stable for up to 1 month at -20°C and for ~8 h at 4°C. Avoid freeze/thaw cycles of solutions.

其他说明

Fleming, I., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 1123.
Olesen, S.P., et al. 1998. Br. J. Pharmacol. 123, 299.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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