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InSolution STAT3 Inhibitor VI, S3I-201-Calbiochem

品牌
Sigma-Aldrich
货号
573130
规格纯度
The InSolution STAT3 Inhibitor VI, S3I-201, also referenced under CAS 501919-59-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation application
参考价格
1763.65 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
InSolution STAT3 Inhibitor VI, S3I-201-Calbiochem
产品介绍:

产品说明

一般描述

A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.).
A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). The solid form of this compound (Cat. No. 573102) is also available.

包装

5 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Irritant (B)

外形

A 50 mM (5 mg/274 µl) solution of STAT3 Inhibitor VI, S3I-201 (Cat. No. 573102) in DMSO.

重悬

Following initial thaw, aliquot and freeze (-20°C).

其他说明

Lin, L., et al. 2009. Oncogene, 28, 961.
Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA104, 7391.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C16H15NO7S
分子量365.36

产品性质

质量水平100
测定≥95% (HPLC)
形式liquid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
protect from light
运输ambient
储存温度−20℃

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)188.6 °F - (refers to pure substance)
闪点(C)87 ℃ - (refers to pure substance)

Sigma-Aldrich

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