6-氯嘌呤

产品名称：

87-42-3
6-Chloropurine
6-氯嘌呤

产品介绍：

产品说明

一般描述

6-Chloropurine (6-CIPH), a 6-substituted purine derivative, is an antileukemic drug. It can be prepared by the chlorination of hypoxanthine with phosphorus oxychloride in the presence of dimethylaniline. The NMR-based conformational analysis of the products formed during the reaction of 6-CIPH with 3,4-di-O-acetyl-D-xylal and 3,4-di-O-acetyl-L-arabinal have been reported. 6-CIPH can undergo palladium-catalyzed cross coupling with organostannanes at 6-position to form the corresponding arylated or alkylated products.

应用

6-Chloropurine may be used:

To prepare purine via catalytic dehydrogenation.
To prepare 9-alkylated adenines via Mitsunobu reaction with various alcohols.
As a starting material to synthesize dihydroisoxazole 6-chloropurine.

包装

5 g in glass bottle

基本信息

经验(实验)分子式	C₅H₃ClN₄
分子量	154.56
Beilstein	5774
EC 号	201-745-6
MDL编号	MFCD00075825
PubChem化学物质编号	24873552

产品性质

质量水平	100
测定	99%
mp	>300 ℃ (dec.) (lit.)
SMILES string	Clc1ncnc2[nH]cnc12
InChI	1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
InChI key	ZKBQDFAWXLTYKS-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves