产品名称：
13754-86-4
1,5,6,7-Tetrahydro-4H-indol-4-one
NSC 131681
4,5,6,7-Tetrahydro-4-oxoindole
1,5,6,7-四氢-4H-吲哚-4-酮
产品介绍：
产品说明
一般描述
Iodination of 1,5,6,7-tetrahydro-4H-indol-4-one using 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) yields α-iodo derivative as the main product.
应用
- Reactant in synthesis of psammopemmin A as antitumor agent
- Reactant in synthesis of a 1,3,4,5-tetrahydrobenzindole β-ketoesters and tricyclic tetrahydrobenzindoles via C-H insertion reactions
- Reactant in preparation of tricyclic indole and dihydroindole derivatives as inhibitors of guanylate cyclase
- Reactant in preparation of condensed pyrroloindoles via Pd-catalyzed intramolecular C-H bond functionalization of (halobenzyl)pyrroles
- Reactant in enantioselective preparation of arylalkenyl indoles via asymmetric C-H insertion of rhodium carbenoids followed by Cope rearrangement-elimination
1,5,6,7-Tetrahydro-4
H-indol-4-one may be used in the preparation of:
- 4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carbonitrile
- methyl 2-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)acrylate
- 3-(4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)propanenitrile
- potent and orally active 5-HT1A agonists, (R)-(+)- and (S)-(-)-1-formyl-6,7,8,9-tetrahydro-N,N-dipropyl-3H-benz[e]indol-8-amines
包装
5 g in glass bottle
基本信息
| 经验(实验)分子式 | C8H9NO |
| 分子量 | 135.16 |
| MDL编号 | MFCD00075438 |
| PubChem化学物质编号 | 24861947 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 100 |
| 测定 | 98% |
| mp | 188-190 ℃ (lit.) |
| SMILES string | O=C1CCCc2[nH]ccc12 |
| InChI | 1S/C8H9NO/c10-8-3-1-2-7-6(8)4-5-9-7/h4-5,9H,1-3H2 |
| InChI key | KASJZXHXXNEULX-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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