产品说明
生化/生理作用
Interleukin-11, also called adipogenesis inhibitory factor (AGIF), is a pleotropic cytokine that acts on hematopoietic progenitor cells and stromal cells. Although recombinant human IL-11 has a predicted molecular mass of 19 kDa, it migrates as a 23 kDa band in SDS-PAGE. It is a functional homolog of IL-6, inducing the proliferation of certain plasmacytoma cell lines and acute phase protein secretion in the liver. IL-11 stimulates the production of erythrocytes, megakaryocytes, and T cell development of antibody producing B cells.
外形
Lyophilized from a 20.0 μL of a 0.2 μm filtered solution in phosphate buffered saline, pH 7.3, with 5% trehalose and with 50 μg bovine serum albumin per 1μg as a carrier protein.
分析说明
Assayed in a cell proliferation assay using T11 cells, a subline of the IL-6 dependent mouse plasmacytoma cell line T1165.85.2, that has been adapted to grow in IL-11.
基本信息
| MDL编号 | MFCD00212208 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 重组 | expressed in E. coli |
| 测定 | >97% (SDS-PAGE) |
| 形式 | lyophilized powder |
| 分子量 | predicted mol wt ~19 kDa |
| 包装 | pkg of 5 μg |
| 杂质 | endotoxin, tested |
| UniProt登记号 | P47873 |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Il11(16156) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
