Interleukin-4 from mouse

产品名称：

Interleukin-4 from mouse
Interleukin-4 human
mIL-4

产品介绍：

产品说明

应用

Interleukin-4 from mouse has been used:

as a component of cell culture media for class switch recombination assay
to study its therapeutic benefits for mucosal healing
as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)

生化/生理作用

Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.

外形

Lyophilized, 0.2 μm filtered, with no additives.

分析说明

The proliferative activity is tested in culture using mouse HT-2 cells.

基本信息

MDL编号	MFCD00166698
NACRES	NA.77

产品性质

生物来源	mouse
重组	expressed in E. coli
测定	≥98% (SDS-PAGE)
形式	lyophilized powder
效能	0.1-2.0 ng/mL ED₅₀/EC₅₀
质量	endotoxin tested
分子量	~13.5 kDa
包装	pkg of 5 μg
technique(s)	cell culture \| mammalian: suitable
杂质	<0.1 EU/μg
UniProt登记号	P07750
储存温度	−20℃
Gene Information	mouse ... Il4(16189)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)