Monoclonal Anti-CXCR2 (IL-8 RB) antibody produced in mouse

产品说明

一般描述

The antibody will neutralize human cell surface CXCR-2 mediated-myloperoxidase release from human granulocytes induced by GROα. It will not block myeloperoxidase release induced by IL-8. The antibody reacts with human CXCR-2 transfectant cells and not the parent cell line. The antibody shows no cross-reactivity with CXCR-1.

免疫原

human CXCR2 transfected NSO mouse myeloma cells.

生化/生理作用

CXCR2 is a G protein-coupled receptor that binds IL-8 with high affinity. It mediates migration of neutrophils to the sites of inflammation. It also binds CXCL1 and stimulates growth of melanomas.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

制备说明

Purified using protein G.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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