N-(3-Pyridyl)indomethacinamide

产品名称：

261766-29-4
N-(3-Pyridyl)indomethacinamide
N-(3-Pyridyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide
N-3PyIA

产品介绍：

产品说明

生化/生理作用

Potent and selective reversible cyclooxygenase-2 (COX-2) inhibitor (IC₅₀ = 0.1 μM, human recombinant); about 300-fold less potent as an inhibitor of human recombinant COX-1. Not as selective with natural ovine COX (IC₅₀ = 75 μM for COX-1 and 50 μM for COX-2).

基本信息

经验(实验)分子式	C₂₄H₂₀N₃O₃Cl
分子量	433.89
MDL编号	MFCD02683393
PubChem化学物质编号	329820062
NACRES	NA.77

产品性质

质量水平	200
测定	≥98%
形式	powder
溶解性	chloroform: 10 mg/mL to clear, colorless to light yellow
运输	wet ice
储存温度	−20℃
SMILES string	COc1ccc2n(c(C)c(CC(=O)Nc3cccnc3)c2c1)C(=O)c4ccc(Cl)cc4
InChI	1S/C24H20ClN3O3/c1-15-20(13-23(29)27-18-4-3-11-26-14-18)21-12-19(31-2)9-10-22(21)28(15)24(30)16-5-7-17(25)8-6-16/h3-12,14H,13H2,1-2H3,(H,27,29)
InChI key	DTAPHQYAZUTCIG-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)