产品说明
应用
PEPTITE-2000® is suitable to coat:
特点和优势
RGD PEPTITE-2000 is used to coat tissue culture plasticware for enhanced cell attachment and adhesion. The product has been specifically developed for ease-of-use for the researcher. It is provided in a 5 mg package size to provide sufficient quantity of product for coating a large surface area. The product has been sterilized and is ready-to-use after proper dilution. The optimal concentration for cell attachment and culture may differ for various cell types. Some experimentation will be required to determine the optimal conditions for individual cell culture systems. A typical working concentration may range from 1 to 100 μg/ml.
其他说明
The tripeptide Arg-Gly-Asp (RGD) is an important protein sequence in the binding of proteins to cell surfaces. The RGD motif was initially identified in fibronectin as the minimal sequence that mediates cell attachment. Research has also shown that the RGD motif in present in other proteins such as vitronectin, osteopontin, collagens, thrombospondin, fibrinogen and many other factors. Many adhesive cell surface receptors recognize the RGD sequence for cell attachment.
Ac-Gly-D-Arg-Gly-Asp-Ile-Pro-Ala-Ser-Ser-Lys-Gly-Gly-Gly-Gly-Ser-D-Arg-Leu-Leu-Leu-Leu-Leu-Leu-D-Arg-NH2
法律信息
PEPTITE-2000 is a registered trademark of Advanced BioMatrix, Inc.
基本信息
NACRES | NA.75 |
产品性质
质量水平 | 200 |
生物来源 | synthetic (organic) |
描述 | RGD Peptide for Cell Adhesion, 5 mg |
无菌性 | electron beam irradiated |
测定 | ≥95% (HPLC) Identity and purity qualitatively determined by (SDS-PAGE) |
形式 | powder |
technique(s) | tissue culture: suitable |
web metadata keyword.default | sigma-aldrich R4658, PEPTITE-2000®,tissue culture plasticware, cell attachment and adhesion. |
运输 | wet ice |
储存温度 | 2-8℃ |
InChI | 1S/C98H174N34O30/c1-48(2)31-60(84(151)120-56(79(100)146)22-17-27-107-96(101)102)124-86(153)62(33-50(5)6)126-88(155)64(35-52(9)10)128-89(156)65(36-53(11)12)127-87(154)63(34-51(7)8)125-85(152)61(32-49(3)4)123-83(150)59(24-19-29-109-98(105)106)122-91(158)67(44-133)119-76(142)42-113-73(139)39-111-72(138)38-112-74(140)40-114-82(149)58(21-15-16-26-99)121-92(159)69(46-135)130-93(160)68(45-134)129-80(147)54(13)116-94(161)71-25-20-30-132(71)95(162)70(47-136)131-90(157)66(37-78(144)145)118-77(143)43-115-81(148)57(23-18-28-108-97(103)104)117-75(141)41-110-55(14)137/h48-54,56-71,133-136H,15-47,99H2,1-14H3,(H2,100,146)(H,110,137)(H,111,138)(H,112,140)(H,113,139)(H,114,149)(H,115,148)(H,116,161)(H,117,141)(H,118,143)(H,119,142)(H,120,151)(H,121,159)(H,122,158)(H,123,150)(H,124,153)(H,125,152)(H,126,155)(H,127,154)(H,128,156)(H,129,147)(H,130,160)(H,131,157)(H,144,145)(H4,101,102,107)(H4,103,104,108)(H4,105,106,109)/t54-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-/m0/s1 |
InChI key | DULMZMHLQQZGPY-ACFXXXONSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich