产品说明
应用
Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 ℃ using a final concentration of 50 μM [32P] ATP.
生化/生理作用
PKCν, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.
外形
Solution of 5 μg in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol
基本信息
MDL编号 | MFCD07371119 |
NACRES | NA.32 |
产品性质
质量水平 | 200 |
重组 | expressed in E. coli |
测定 | ≥75% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
分子量 | protein apparent mol wt ~142 kDa |
UniProt登记号 | O94806 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... PRKD3(23683) |
Sigma-Aldrich