产品说明
一般描述
Protein kinase, cGMP-dependent, type II (PRKG2), also known as type II cGMP-dependent protein kinase (cGK), is encoded by the gene mapped to human chromosome 4q13.1–q21.1.
生化/生理作用
Protein kinase, cGMP-dependent, type II (PRKG2) is implicated in the regulation of intestinal fluid balance in man. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism.
单位定义
One unit will phosphorylate one μmole of VASPtide (RRKVSKQE) per minute at pH 7.4
基本信息
| MDL编号 | MFCD03444648 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 重组 | expressed in baculovirus infected Sf9 cells |
| 测定 | >90% (SDS-PAGE) |
| 形式 | solution |
| specific activity | ~0.7 U/mg |
| UniProt登记号 | Q64595 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | rat ... Prkg2(25523) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
