产品说明
包装
5000 units in glass bottle
生化/生理作用
An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.
单位定义
One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25℃.
制备说明
Cloned from E. coli and produced in overexpressing E. coli
基本信息
| 酶学委员会(EC)编号 | 2.4.2.4 ( BRENDA | IUBMB ) |
| MDL编号 | MFCD00132426 |
| NACRES | NA.54 |
产品性质
| 重组 | expressed in E. coli |
| 质量水平 | 400 |
| 形式 | buffered aqueous solution |
| 浓度 | ≥500 units/mL |
| application(s) | diagnostic assay manufacturing |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
