产品说明
生化/生理作用
ASF also known as SF2 is a member of the SR protein family. It is an essential pre-mRNA splicing factor required for both single and alternative splicing. Phosphorylation on serine residues located within the SR domain directly regulates ASF/SF2 activity and compartmentalization of other SR splicing factors. In addition to interacting with RNA and other splicing factors, such as U1-70K, U2AF and other SR proteins, ASF/SF2 also directly or indirectly interacts with HIV regulatory protein Rev, the C-terminal domain (CTD) of the largest subunit of RNA polymerase II, and numerous transcription factors, thereby suggesting a potential role of ASF/SF2 in coordinating transcription and pre-mRNA splicing.
外形
Clear and colorless frozen liquid solution
制备说明
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
产品性质
| 生物来源 | human |
| 重组 | expressed in insect cells |
| 测定 | ≥85% (SDS-PAGE) |
| 形式 | frozen liquid |
| 分子量 | ~29.3 kDa |
| 包装 | pkg of 5 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 浓度 | 350 μg/mL |
| 颜色 | clear colorless |
| NCBI登记号 | NM_006924 |
| UniProt登记号 | Q07955 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... SRSF1(6426) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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