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Edelfosine

品牌
Avanti
CAS
77286-66-9
货号
999995P
规格纯度
1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine, powder
参考价格
1192.61 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
77286-66-9
Edelfosine
产品介绍:

产品说明

应用

Edelfosine or 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine might be used:

  • as a non-hydrolysable LysoPC (phospholipid) analog for analyzing its ability to block sexual commitment in Plasmodium falciparum
  • in multilamellar vesicle preparation, to study its effect on model membranes
  • in the selection and screening of mutagenized cells, having the ability to inhibit the transport of alkylphosphocholine drugs across the plasma membrane

生化/生理作用

Edelfosine acts as a precursor for alkyl-lysophospholipids. It possesses apoptotic action against several cancer cells such as prostate, leukemia, brain and lung tumors. It is associated with cellular transport system, signaling transducing systems, cytokine synthesis and lipid metabolism. Edelfosine is known to control intracellular calcium levels. It is not mutagenic and its anti-tumor action requires its incorporation into the cell. Edelfosine is also found to block the replication of human immunodeficiency virus type I (HIV-I).

包装

5 mL Clear Glass Sealed Ampule (999995P-5mg)

基本信息

经验(实验)分子式C27H58NO6P
分子量523.73
NACRESNA.25

产品性质

形式powder
包装pkg of 1 × 5 mg (999995P-5mg)
manufacturer/tradenameAvanti Polar Lipids 999995P
运输dry ice
储存温度−20℃
SMILES string[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC)COCCCCCCCCCCCCCCCCCC)=O
InChI1S/C10H24NO5P/c1-6-10(14-5)9-16-17(12,13)15-8-7-11(2,3)4/h10H,6-9H2,1-5H3/t10-/m0/s1
InChI keyGVMCXWJIRSIWFJ-JTQLQIEISA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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