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p53 (1-363) C-terminal deletion human

品牌
Sigma-Aldrich
货号
SRP2077
规格纯度
recombinant, expressed in insect cells, ≥80% (SDS-PAGE)
参考价格
6866.13 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
p53 (1-363) C-terminal deletion human
TRP53
LFS1
P53
FLJ92943
产品介绍:

产品说明

生化/生理作用

Human p53 protein is composed of 393 amino acid residues with several distinct regions. The N-terminal activation domain allows p53 protein to recruit the basal transcription machinery and activate the expression of target genes, whereas the core domain binds to target DNA in a sequence-specific manner and the majority of mutations found in human tumors occur in the region of the gene encoding this domain. The C-terminal domain is composed of predominantly basic residues and modification of the C-terminal basic domain, including acetylation, glycosylation and phosphorylation, is an essential mechanism for regulating p53 function.

外形

Clear and colorless frozen liquid solution

制备说明

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

基本信息

NACRESNA.26

产品性质

生物来源human
重组expressed in insect cells
测定≥80% (SDS-PAGE)
形式frozen liquid
分子量 ~41.8 kDa
包装pkg of 5 μg
浓度850 μg/mL
颜色clear colorless
NCBI登记号NM_000546
UniProt登记号P04637
运输dry ice
储存温度−70℃
Gene Informationhuman ... TP53(7157)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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