β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid

产品名称：

125464-42-8
Saclofen
β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid

产品介绍：

产品说明

应用

Saclofen has been used as a GABA_B receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.
Saclofen has been used to prevent the inhibitory action of oxytocin on capsaicin-induced glutamatergic spontaneous excitatory transmission in rat neurons.

包装

5 mg in glass bottle

生化/生理作用

Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.
Saclofen is the sulphonic analog of baclofen and is a selective GABA_B receptor antagonist.

基本信息

经验(实验)分子式	C₉H₁₂ClNO₃S
分子量	249.71
MDL编号	MFCD00216817
PubChem化学物质编号	329824485
NACRES	NA.32

产品性质

质量水平	200
形式	solid
颜色	white
溶解性	0.1 M NaOH: 20 mg/mL
SMILES string	NCC(CS(O)(=O)=O)c1ccc(Cl)cc1
InChI	1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)
InChI key	JYLNVJYYQQXNEK-UHFFFAOYSA-N
Gene Information	human ... GABBR1(2550), GABBR2(9568) mouse ... GABBR1(54393), GABBR2(242425) rat ... GABBR1(81657), GABBR2(83633)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)