产品说明
生化/生理作用
SC35, a member of the SR protein family, is an essential pre-mRNA splicing factor and can function as an essential splicing factor as well as an alternative splicing factor. Phosphorylation of serine residues located within the SR domain directly regulates SC35 activity and compartmentalization of other SR splicing factors. In addition to interacting with RNA and other splicing factors, SC35 has been shown to interact either directly or indirectly with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II, thereby suggesting a potential role of SC35 in coordinating transcription and pre-mRNA splicing.
外形
Clear and colorless frozen liquid solution
制备说明
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
基本信息
NACRES | NA.26 |
产品性质
生物来源 | human |
重组 | expressed in insect cells |
测定 | ≥80% (SDS-PAGE) |
形式 | frozen liquid |
分子量 | ~27 kDa |
包装 | pkg of 5 μg |
储存条件 | avoid repeated freeze/thaw cycles |
浓度 | 650 μg/mL |
颜色 | clear colorless |
NCBI登记号 | NM_003016 |
UniProt登记号 | Q01130 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... SRSF2(6427) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich