产品说明
一般描述
17:0(2R-OH) Ceramide is a 2R hydroxylated heptadecanoic acid-containing sphingolipid. It is present mainly in epidermis.
生化/生理作用
Hydroxy fatty acids (hFA)-sphingolipids play a vital role in cell signaling. They also help in cell differentiation and apoptosis. hFA-ceramides are involved in the formation of the epidermal barrier. Fatty acid 2-hydroxylases (FA2H) synthesize hFA-ceramides. Mutations of FA2H have been linked to neurological disorders like spastic paraparesis in humans and leukodystrophy. hFA-ceramides in the cell membrane play a crucial role in imparting the PM02734 drug with anti-tumor activity.
包装
5 mL Amber Glass Screw Cap Vial (860817P-5mg)
基本信息
| 经验(实验)分子式 | C35H69NO4 |
| 分子量 | 567.93 |
| NACRES | NA.25 |
产品性质
| 形式 | powder |
| 包装 | pkg of 1 × 5 mg (860817P-5mg) |
| manufacturer/tradename | Avanti Polar Lipids 860817P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCC)=O)CO |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
Sigma-Aldrich
m.cnreagent.com
